PRODUCT MONOGRAPH. PR. Cathflo. ® alteplase, recombinant . cell line into which the cDNA for alteplase has been genetically inserted. Read all of this leaflet carefully before you What Actilyse Cathflo is and what it is used for. 2. Contents of the pack and other information. 1. Drug monographs for CATHFLO ACTIVASE provide an overview of the drug Keeping the vial of Sterile Water for Injection upright, insert the piercing pin of the .

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Hello, We occasionally use Cathflo Activase for central lines, e. The package insert says to assess catheter function after 30 minutes of dwell time, and if there is no blood return after 30 minutes, it says to assess “after a total of minutes of dwell time We often check for a blood return after 60 minutes if there is no blood return at 30 minutesbut if there is still no blood return, we typically report this and request an order to treat the patient in the absence of a blood return of course, we would have assessed how the port flushes, for any other signs of problems, and would not administer a vesicant agent in the absence of a blood return.

Does anybody allow the Cathflo to dwell for up to the full minutes?

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We don’t want to “give up” too soon if practices are actually waiting this long and seeing positive results, but “chair time” may be a concern, particularly if the patient is scheduled for a long treatment that day. Several years ago, our outpatient clinic would leave the Cath-Flo in for up to 24 hours in cases where the patient would not be able to wait for the 2 hours in the clinic.

It usually was for patients who had to go to radiation since our rural facility does not have a radiation unit nearby Our patients have to travel about 30 or more miles one way to get to a facility. We had great success with this. We now just follow the manufacturer’s recommendations of 30 minutes to 2 hours of indwelling time.

We get a dye study for any port that does not have a blood return and use them if the radiologist’ report states they are in the proper place pacckage ok to use. Bloomington St, Greencastle,IN Skip to main content Press Enter. Skip auxiliary navigation Press Enter. Skip main navigation Press Enter.

Date range on this day between these dates. Expand all Collapse all sort by most recent sort by thread. Question about dwell time of Inssert Activase for central lines. If wait time is an iss We do as the manufacturer recommends; check after 30 mins and then at the end of a 2 he dwell.


Leave it for the full ! When I leave for the full dwell time I almost always have result. I usually get blood return after a max of 60 minutes, luckily have never had to wait the full Hi Our policy is to to a dye study if there is no blood return after minutes. We do not trea Thank you to all who responded to my post and for the helpful information about catjflo other practices We have commonly left the Agree with leaving cath flow for minutes if doesn’t clear out the first time.

I must ask the question as I inxert hearing lots of rumble from my in-patient colleagues about Several years ago, our outpatient clinic would leave the Cath-Flo in for up to 24 hours in cas I say always follow the pharmaceutical company guidelines since they have the data.

I can not find any in Our standardized procedure pro If wait time is an issue we get an order for a chest xray to confirm proper portacath placement. If it shows that placement is correct then we get a Md order to proceed. I hope this was helpful to you. If there is still no blood return, a catheter dye study will be ordered.

We have an institutional policy that as long as the dye study shows it is in place, we can use it. We have a few patients who are fibrin producers, so form the sheath. If not, we ask for insret second dose of alteplase with results. I had an inservice earlier this year and learned a ton. If you have time, don’t bother checking after the first 30 minuets. Let me know if you have further questions! To save time and hassle, and patient caghflo issues, we send the patient home after Cathflo is instilled, and have them back the next day.

We follow the manufacturer’s instructions of allowing a dwell time up to minutes checking periodically after 30 minutes for blood return. We have not had any problems related to this that I am aware of and in fact, I have seen catheters that did not work after 30 and 60 minutes, have great blood return after minutes.

Delays in treatment are always a concern when you have a clotted catheter. In an outpatient unit, I can imagine this greatly affects turn around time and the number of patients you can treat daily, etc. I am not an expert in outpatient care, but I would think that you have to take this on a case by case and day to day basis. If you can obtain other IV access, then give the treatment there and simultaneously ctahflo the cath-flo to dwell and work to de-clot the port.


Hopefully if it is de-clotted properly at that treatment, it will function properly for the next treatment. Most patients are usually agreavms and this has helped to prevent delays. We do not treat before we are assured that the line is patent and in the right place. Thank you to all who responded to my post and for the helpful information about how inxert practices manage Cathflo Activase for their central lines.

We have commonly left the cath flo in for up to minutes if not successful on first check and it has worked.

Cathflo Activase (alteplase) dose, indications, adverse effects, interactions from

We have also found this really works and have never had one not return blood after the minutes. I must ask the question as I am hearing lots of rumble from my in-patient colleagues about 24 hour dwell time.

This would require in the out-patient setting sending the patient home with the port accessed and Alteplase dwelling. The patient would then return to the Clinic for aspiration and flush. I have seen no official recommendation and no study or data, but I have had multiple discussions about this practice as an effective alternative to catheter stripping or replacement due to fibrin sheath that does not respond to 2 hour dwell.

My attempts to identify any research or even anecdotal data have not been successful and I’d be really interested in your thoughts. In my experience, one hour dwell is what we usually need. That is what I generally go with and it almost always works. I can not find any information as I believe it is off label. Has anyone done this? I found one instance where they infused 2mg over a 24 period?

Here is an example for declotting a dialysis cath: Wible and his expert author team provide carefully updated information in a concise, bulleted format, keeping you current with recent advances in interventional radiology. We then would wait up to min and if still occluded we then try a 2nd dose of Alteplase of an equal amount and begin the process again. Although we only use a total of 2 Alteplase doses in a 24hr time period.

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